Ardelyx (ARDX) Is Down 16.3% After Issuing Higher 2026 Product Revenue Guidance and Patent Update

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Ardelyx (ARDX) shares fell 16.3% despite the company issuing higher 2026 product revenue guidance for IBSRELA (US$410–US$430 million) and XPHOZAH (US$110–US$120 million) and announcing new patent protection until 2042. The company reported full-year 2025 revenue of US$407.32 million but a widened net loss of US$61.6 million, with its investment narrative emphasizing continued revenue growth but flagging ongoing unprofitability due to rising R&D and SG&A costs. Analysts had previously projected significantly higher 2028 revenues and earnings for Ardelyx, which may now be adjusted following this guidance.

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