Prediction: Buying Pfizer Stock Today Could Set You Up for Life

Pfizer (PFE 1.87%) investors got some very bad news when the company was forced to abandon its internally developed GLP-1 weight loss drug in April, 2025. With patent expirations on the horizon, falling even further behind competitors like Novo Nordisk (NVO 1.07%) and Eli Lilly (LLY 2.12%) in an emerging new drug niche was a bad look. However, what happened next is what’s really important.

Pfizer quickly changes course in the GLP-1 space

GLP-1 drugs have seen strong consumer demand. Eli Lilly’s industry-leading GLP-1 drugs Mounjaro and Zepbound, for example, saw revenue growth of 99% and 175%, respectively, in 2025. The flameout of Pfizer’s internally generated GLP-1 candidate was a major setback.

Image source: Getty Images.

In fact, Pfizer hasn’t exactly been hitting out of the park for a while. Its COVID vaccine success is well in the past, and it has notable patent expirations coming up over the next couple of years. The stock is down around 50% from its 2021 highs. That said, Pfizer didn’t give up on the GLP-1 niche. It quickly shifted gears, buying a company with a promising GLP-1 candidate. The deal closed in November, 2025, less than a year after Pfizer announced its own weight loss drug had been dropped. That’s a pretty quick pivot.

Pfizer is still an industry giant

What’s interesting here is that, despite a massive decline in value, Pfizer still has a market cap of $150 billion. It is a well-respected industry giant navigating the normal ebbs and flows of the pharmaceutical industry. Innovation is vital, but it doesn’t come in a smooth line. And, sometimes, a company’s plans don’t work out as well as hoped.

Expand

NYSE: PFE

Pfizer

Today’s Change

(-1.87%) $-0.52

Current Price

$27.05

Key Data Points

Market Cap

$154B

Day’s Range

$27.02 - $27.77

52wk Range

$20.91 - $27.94

Volume

1M

Avg Vol

45M

Gross Margin

66.23%

Dividend Yield

6.36%

It is what happens during the hard times that defines a drug company. In February 2026, less than a year after its own drug was dropped, Pfizer announced that the long-acting GLP-1 drug it is now working on was progressing as hoped. That’s the sign that Pfizer hasn’t suddenly lost its way. It is still the industry-leading drugmaker it was back when COVID vaccines were driving the stock higher.

Long-term investors should consider Pfizer

Pfizer’s dividend yield is a lofty 6.2%, largely because its payout ratio is over 100%.​​ Conservative dividend investors may want to tread with caution. However, management has stated its intention to maintain the dividend. All in, if you think in decades, this out-of-favor drug stock is still an industry leader. It could easily help set you up for life and, likely, for a lifetime of dividends.